Nanofibres in Drug Delivery Applications
نویسندگان
چکیده
Over the years, scientists have been continually striving to develop innovative solutions design and fabricate medicines with improved therapeutic potential. Conventional dosage forms, such as tablets, capsules, injections, are limited when exploited for advanced therapeutics, drug targeting. To cater these limitations, nanofibres emerged novel nanomaterials provide enhanced bioavailability, targeted release, extended release profile, minimum toxicity, reduced frequency, which has indisputably patient adherence compliance. This review will concern understanding potential of drug-loaded in delivery while comprehending a detailed description their different production methods. The literature thoroughly reviewed appreciate developing nanofibrous-based pharmaceutical formulations. Overall, this highlighted importance, versatility, adaptability varied kinetics. Several problems must be resolved full commercial realisation, loading, initial burst effect, residual organic solvent, stability active agents, combined usage new or existing biocompatible polymers.
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ژورنال
عنوان ژورنال: Fibers
سال: 2023
ISSN: ['2079-6439']
DOI: https://doi.org/10.3390/fib11020021